A couple can try IVF as many times as they want while keeping the treatment cost in mind.
As long as you are in close contact with the clinician, having your tests done at a clinic near you is feasible. Expert doctors from Zemya IVF work in many cities & 7+ IVF centres across India so that patients in far rural areas can also access the best fertility care with ease.
The process is not painful as it is done under mild sedation. But, a few times it may cause mild discomfort. At Zemya IVF & Fertility Clinics, we use mild anaesthesia administered through an IV route which relieves discomfort.
Success rates vary depending on different factors such as the age of the patient, their condition, medical history and the line of treatment administered.
The IVF procedure can be opted in cases where the other fertility treatments have failed, or if the chances of a successful pregnancy are higher with IVF than with any other treatment. If there are no contraindications, the IVF procedure can be carried out simply at the request of the couple.
IVF is a very safe and painless procedure because the injections used are purified and administered subcutaneously. The egg collecting procedure is performed under minimal sedation, which is also not uncomfortable. Anaesthesia is not used during embryo transfer because the procedure lasts about 2 to 5 minutes and is relatively painless. When performed under competent supervision, IVF can be a very safe and simple operation.
Every patient is unique, thus the method will vary from one to the next. However, IVF injections are thin, simple, and do not require assistance. They can also be given under anaesthesia if necessary. The egg collecting procedure is performed under minimal sedation, which is also not uncomfortable. Anaesthesia is not used during embryo transfer because the procedure lasts about 2 to 5 minutes and is relatively painless.
Tubal-peritoneal factor - When the fallopian tubes' patency is violated, the egg is unable to enter the uterus. In this situation, you can either undergo IVF and implant an already-developing embryo into the uterus or attempt to restore patency by a surgical laparoscopic procedure. In this situation, you have two options: either undertake IVF and implant an already-developing embryo into the uterus, or attempt to restore patency with a surgical laparoscopic procedure.
Male factor - When the quality of sperm is not high enough. If the number of healthy sperm is too low to conceive a healthy child, it is better to offer ART treatments like IVF, IUI, ICSI, etc.
Endometriosis - Hormonal therapy and surgery are typically effective in treating mild endometriosis. The doctor refers the couple for an IVF procedure if pregnancy is not achieved following therapy.
Age-related infertility - Age plays a critical role when we talk about deciding the right time for IVF. With age as a factor of infertility, it is better to supplement the standard IVF procedure with ICSI and assisted hatching methods.
Anovulation - Anovulation is normally treated with simpler treatments, such as hormonal stimulation paired with IUI, but if that fails, IVF is always an option. However, if it fails, you can always try IVF.
Unexplained infertility - Sometimes it is not possible to establish an accurate diagnosis, and the therapy is unsuccessful, then the doctor may advise the couple on advanced fertility treatments like IVF procedure.
In this procedure, the female egg is extracted under anaesthesia and fertilised in the laboratory with the husband's sperm. After 3-5 days, the embryo is put back into the uterus.
It may take 2-3 visits: One day for check-up or Pre-IVF preparation 15 days for IVF procedure (Second Visit) Embryo transfer
Resting for 15-20 minutes after the transfer is generally sufficient. We advise avoiding strong activities and long walks during this time. Women who work in an office can return to work the next day and continue with their usual routines.
IVF is scheduled for the second time only after a comprehensive evaluation and examination of potential causes of failure. As an IVF cycle gap, a lady is provided an average of three months of recovery. During this time, the reproductive system is rebuilt and ready to receive a newly fertilised egg. If the initial IVF resulted in a frozen pregnancy, the rest period will last approximately 6 months. In such cases, persistent endometritis is almost always present, necessitating meticulous treatment before attempting a new pregnancy.
To make the second attempt successful, modest tweaks to the prior IVF protocol, such as adding a correct IVF cycle gap, may be sufficient. In certain circumstances, a long stimulation cycle is replaced by a short one, or one hormonal preparation is substituted for another, and in others, the dosage is altered.
If no specific difficulties were discovered and the first IVF attempt was carried out in a normal cycle, without hormonal stimulation, the artificial insemination operation can be performed after two weeks. This means that throughout the next menstrual cycle, doctors begin to monitor the dominant follicle and, when favourable conditions are met, perform a puncture and egg collection.
Walking and modest aerobic workouts are fine, but avoid lifting big weights and rigorous exercises.
▪ After embryo transfer, there is no need for bed rest; nonetheless, avoid hard lifting and severe workouts.
▪ Maintain a nutritious diet rich in antioxidants and avoid eating out.
▪ Avoid using public restrooms and stay hydrated to prevent urinary tract infection.
▪ Avoid stressful and negative thoughts.
▪ Comply with prescribed drugs following embryo transfer.
Even though an embryo is created artificially during an IVF pregnancy, the process is identical to what occurs naturally. The uterus accepts embryos in the same way as it receives naturally fertilised eggs.
It is critical to recognise that nature has a failsafe strategy in everything, including the reproductive system, in which the embryo firmly attaches to the uterine lining whether naturally or artificially. Walking and gravity do not cause the embryo to detach and fall off.
Also, it is a complete misconception that bed rest following embryo transfer improves IVF success rates. According to research, individuals who take total bed rest following embryo transfer have lower IVF success rates than patients who continue to undertake their usual activities. The fundamental reason for this is that patients who engage in these activities have reduced stress levels, which improves their chances of IVF success. As a result, the recommendation of bed rest following embryo transfer is overstated or unrealistic.
At Zemya IVF & Fertility Clinics, the cost of IVF/ICSI therapy varies by cycle. It is best to speak with our fertility specialist for a personalised treatment plan.
*All costs for the IVF process, injections, egg pickup, and embryo transfer are included. The cost of therapy varies depending on your test results, the type of treatment necessary, hormonal problems, and other factors, and it may differ between couples.
This procedure demands highly qualified workers, a world-class laboratory, and cutting-edge equipment. All of the equipment and supplies used in IVF labs are imported and pricey. Furthermore, the majority of the materials utilised are disposable and intended to be used once.
The cost of the IUI program at Zemya IVF & Fertility Clinics varies by cycle.
*The cost of therapy is determined by your test results, the type of treatment necessary, hormonal conditions, and other factors, and may vary from couple to couple.
The process of IVF involves the following series of steps. They include;
1. Consultation.
You are required to have consultations with the specialist conducting the IVF procedure. Following consultations, the professional will advise you accordingly based on the discussion that takes place.
2. Tests and ovarian stimulation
The ovarian stimulation process starts when your period comes, unlike the normal case whereby it starts after 6 days when the period ceases. You will receive drugs for up to 8-14 days to increase eggs within your ovary.
3. Eggs retrieval.
This process takes approximately 20-30 minutes while under sedation. Your specialist uses ultrasound techniques and needle to retrieve eggs from your ovaries. The average number of eggs retrieved is between 8 and 15.
4. Sperm retrieval.
If a couple intends to use fresh sperm in an IVF treatment method, sperm retrieval takes place on the same day as egg retrieval. In the case of frozen or donor eggs, the specialists will prepare them in the lab.
5. Fertilisation
The scientists will now use sophisticated microscopes to separate the eggs from the fluid. The eggs and sperm are then fertilised in a dish under in vitro conditions.
6. Embryonic development
Once the egg fertilises the sperm, the process forms a zygote that develops further into an embryo. This embryo will then be incubated in a special incubator.
7. Transfer of embryo
The scientist will prepare the embryo and insert it inside a catheter. The catheter will then be inserted through your cervix into your uterus.
8. Final pregnancy test
After two weeks from your embryo transfer, your specialist will take a blood test to check your hCG levels. If your blood tests positive for hCG, this is an indication of a successful pregnancy.
Intrauterine insemination (IUI) is one of the most common techniques used in ART. This technique allows the sperm to be placed directly inside the womb of the woman. During this process, washed sperm is used. With the help of this process, chances for conception increase.
ICSI is one of the standard IVF techniques that utilise a new strategy for fertilising the egg. When the sperm comes into contact with the egg and goes through its outer membrane, this is termed fertilisation. There could be situations where the sperm fails to enter the egg. In such cases, the use of ICSI and IVF procedures can help conceive. The ICSI process entails selecting a single sperm and injecting it directly into the egg.
ICSI is carried out by an experienced embryologist using specialised equipment. Though ICSI is a precise method for fertilisation to occur, certain biological activities must take place.
Oligospermia is another term for having a low sperm count. One can have ICSI (Intracytoplasmic Sperm Injection), in which a single sperm is put into a mature egg. Adapting this treatment increases the odds of conceiving. Aside from that, ICSI is effective, particularly in cases of male infertility, low sperm motility, and poor sperm morphology.
For guys who do not have sperm, there are procedures such as TESA/TESE. These involve taking tissue samples directly from the testes in various ways according on the disease. If sperm is detected in the tissue samples, ICSI can be utilised to fertilise the eggs.
The duration of this treatment is solely determined by the number of follicles that must be sucked. Normally, it takes between 5 and 10 minutes.
Cryopreservation is the freezing of eggs, sperm, or embryos for later use. In IVF, three types of cryopreservation procedures are used.
(i) oocyte cryopreservation or egg freezing-
Oocyte cryopreservation permits you to use frozen eggs at any time in the future. When you're ready to get pregnant, use these preserved eggs to ensure a healthier pregnancy. This alleviates your fears about chromosomal abnormalities, which often rise with age, particularly if you are 35 or older. Frozen oocytes can be thawed and mixed with sperm in a clinical lab.
(ii) Sperm cryopreservation is the method of storing sperm for later use. It assists men in preserving their fertility who are set to undergo a treatment that may cause fertility problems, such as cancer therapy or prostate or testicular surgery. If you are at risk of being exposed to chemicals or radiation, you may want to consider sperm freezing. This method is also utilised for sperm banking.
(iii) Embryo Cryopreservation- Embryo cryopreservation is an effective method for conserving fertility for future use in IVF. Many times, excess embryos from an IVF round are preserved for later use. If IVF fails the first time, embryo cryopreservation allows you to try again. You will not need to go through the entire IVF procedure again.