PGT-M, or Preimplantation Genetic Testing for Monogenic Disorders, is an advanced genetic test performed during IVF to detect embryos that carry specific inherited genetic diseases. These are single-gene conditions such as thalassemia, sickle cell anemia, cystic fibrosis, and Huntington’s disease.
PGT-M allows only genetically unaffected embryos to be selected for transfer, helping prevent the transmission of serious genetic disorders. At Zemya IVF & Fertility Clinics, we offer PGT-M testing in Delhi as part of our comprehensive and ethical fertility care.
PGT-M is especially recommended for couples or individuals who:
Zemya IVF & Fertility Clinics provides genetic counseling to help determine whether PGT-M is necessary in your case.
A blood sample is collected from both partners. Genetic testing is performed to identify the specific gene mutation. A customized probe is developed for your unique condition, which may take 4 to 6 weeks. In some cases, DNA from family members may also be required.
The female partner (or egg donor) undergoes ovarian stimulation. Eggs are collected and fertilized with sperm using ICSI in the IVF lab. Embryos are grown to the blastocyst stage (day 5 or 6).
A few cells are gently removed from the outer layer (trophectoderm) of each embryo. The embryos are frozen until test results are received.
The biopsied cells are sent to a genetics lab. Using the custom probe, each embryo is tested to determine whether it is affected, a carrier, or unaffected.
Only unaffected embryos are chosen for transfer. In certain cases, carrier embryos may be considered, depending on the condition and risks involved.
After transfer, a blood test is done 12–14 days later to confirm pregnancy. Regular scans and prenatal care follow
Despite these limitations, PGT-M is the most reliable method to avoid the inheritance of known single-gene disorders.
The cost of PGT-M in India varies depending on several factors:
At Zemya IVF & Fertility Clinics, we provide PGT-M testing at accessible pricing, with full transparency. Our team ensures that you're informed of your options and costs at every step.
At Zemya IVF & Fertility Clinics, we design each treatment plan around your specific needs and medical history.
With over 40+ years of combined experience and more than 10,000 healthy deliveries, our team is committed to helping you achieve your dream of parenthood with skill, care, and compassion.
Here’s what makes Zemya IVF & Fertility Clinics one of the top 5 IVF and fertility centres in Delhi:
Each treatment is designed specifically around your medical history, goals, and emotional needs.
Our doctors and embryologists are internationally accredited and bring decades of hands-on fertility experience to every case.
We explain everything clearly—no hidden fees, no unnecessary procedures.
Get access to the best care at a cost that respects your budget.
From lab facilities to diagnostic equipment, we use the latest in reproductive science to increase your chances of success.
Whether you’re just starting out or seeking a second opinion, Zemya IVF & Fertility Clinics is here to guide you every step of the way, with experience you can trust, and care you can feel.
PGT-M tests for specific genetic diseases (single-gene mutations). PGT-A checks for chromosomal number abnormalities such as Down syndrome.
No. PGT-M requires IVF because embryos need to be tested before being transferred.
No. With skilled embryologists, the biopsy procedure is safe and does not harm the inner part of the embryo that develops into the baby.
If no healthy embryos are available, the couple may consider another IVF cycle, using donor gametes, or receiving further genetic counselling.
Initial genetic mapping and custom probe development can take 4–6 weeks. The testing and embryo analysis are completed after the IVF cycle.
Yes. As long as the specific gene and mutation are identified, custom testing can be developed—even for rare disorders.
PGT-M is highly accurate for the targeted condition, but no test can guarantee a perfectly healthy baby. Prenatal screening is still advised during pregnancy.
Book your free consultation today and take the first step toward building the family you’ve always dreamed of, with one of the best and most affordable IVF clinics in Delhi.